TOKYO, JAPAN - September 19, 2017 - Terumo Corporation (TSE: 4543) announced today that it has launched QuiremSpheres® microspheres on September 18 in Europe. QuiremSpheres® are available in Europe with plans for expansion its sales area outside of Europe in the future.
QuiremSpheres®, the next generation of SIRT microspheres, are indicated for the treatment of advanced unresectable liver tumors and are the only commercially available microspheres that contain the radioactive isotope Holmium-166. Recent trials have shown the safety and efficacy of holmium microspheres for the treatment of advanced liver cancer. Unlike the widely adopted Yttrium-90 microspheres, QuiremSpheres® can be visualized in low concentrations by means of SPECT and MRI. This allows clinicians to quantitatively assess the distribution of microspheres in the liver, enabling accurate evaluation of treatment directly after SIRT procedure. The half-life of QuiremSpheres® is 26.8 hours, which means that more than 90% of the radiation is delivered within the first 4 days following the implantation procedure.
Peter Coenen, President of Interventional systems Terumo EMEA said: "Terumo is one of the world's leading company in the interventional oncology field offering micro catheters, bland embolization beads, and many other related products. We are grateful to offer new treatment options to physicians and patients. We believe Quiremspheres® enhances our position to be trusted as a top brand in the interventional oncology field."
About Quirem Medical BV
Quirem Medical is an emerging medical device company with a mission to develop the next generation microspheres for targeted interventional treatment of liver malignancies. It is based in Deventer, the Netherlands and is a spin-off company from the University Medical Center in Utrecht.
The recommended whole liver dose of 60Gy was identified as the maximum tolerated radiation dose in a phase I trial (no dose-limiting toxicity occured in the 60Gy cohort) Smits et al, Lancet Oncol. 2012, Oct;13(10):1025-34. ClinicalTrials.gov Identifier: NCT01031784
Study results have been published in PhD thesis of J.F. Prince; ISBN 978-90-393-6489-5; 2016. ClinicalTrials.gov Identifier: NCT01612325
Terumo (TSE: 4543) is a global leader in medical technology and has been committed to “Contributing to Society through Healthcare” for 100 years. Based in Tokyo and operating globally, Terumo employs more than 28,000 associates worldwide to provide innovative medical solutions in more than 160 countries and regions. The company started as a Japanese thermometer manufacturer, and has been supporting healthcare ever since. Now, its extensive business portfolio ranges from vascular intervention and cardio-surgical solutions, blood transfusion and cell therapy technology, to medical products essential for daily clinical practice such as transfusion systems, diabetes care, and peritoneal dialysis treatments. Terumo will further strive to be of value to patients, medical professionals, and society at large.