News release

Tokyo ― Terumo Corporation (TSE: 4543 Section 1) announced CE marking for the commercial sale of the Iberis™ Renal Sympathetic Denervation System, which the company has consigned product development to Shanghai AngioCare Medical Technology Co., Ltd. (hereinafter "AngioCare") (Representative: Philip Wang), a Chinese company in renal sympathetic denervation technology for resistant hypertension treatment.
In December, 2012, Terumo formed a strategic alliance with AngioCare. Furthermore, the company has consigned product development to AngioCare and acquired the exclusive distribution rights for its renal sympathetic denervation technology on the global market.
Sales of Iberis in Europe will be commenced with its launch at the world's leading cardiovascular intervention course, "EuroPCR" to be held in France in May, 2013.
Terumo aims to expand its renal sympathetic denervation business by launching Iberis in Asian and Latin American countries where the CE marked product is allowed for commercialization.
Renal sympathetic denervation
The renal sympathetic nerve plexus is a major contributor of hypertension. During renal sympathetic denervation, a catheter is introduced using standard interventional technique via the femoral artery, and is positioned in the renal artery under fluoroscopic guidance. The electrode at the distal tip of the catheter delivers high radio frequency through the wall of renal artery to ablate or disrupt the surrounding renal sympathetic nerves lying in the vessel. Renal sympathetic denervation using a catheter-based technique is highly expected to be a new, effective treatment option for the many patients with hypertension who do not respond to conventional drugs, or "resistant hypertension".

About Terumo
Terumo (TSE: 4543) is a global leader in medical technology and has been committed to “Contributing to Society through Healthcare” for 100 years. Based in Tokyo and operating globally, Terumo employs more than 28,000 associates worldwide to provide innovative medical solutions in more than 160 countries and regions. The company started as a Japanese thermometer manufacturer, and has been supporting healthcare ever since. Now, its extensive business portfolio ranges from vascular intervention and cardio-surgical solutions, blood transfusion and cell therapy technology, to medical products essential for daily clinical practice such as transfusion systems, diabetes care, and peritoneal dialysis treatments. Terumo will further strive to be of value to patients, medical professionals, and society at large.